Special Offer for $249

Login Image

Mindscape Rx
Membership

$299
$249/Monthly

Includes monthly medication supply and routine provider check-ins. Discount void upon cancellation of membership.

Special founding member price - only for the first 500 customers! Sign up now to lock in this price for the next two years!

Unlock The Power Of Ketamine

science-shade science-shade

It’s all in the science

Why is ketamine therapy so effective? Can a medication really shift how you think and see the world?

Ketamine really does cause positive changes inside the brain, enhancing neural processes related to emotional processing and learning.

Repair your brain,
improve your mood fast

Depression, anxiety, and PTSD are associated with chronic stress, a condition that causes a loss of neural connections, or synapses, within the brain. The neurotransmitter glutamate plays a role in “brain plasticity”, or the regrowth and repair of neurons and synapses. The glutamate system also contributes to learning, memory, and mood regulation.

Ketamine causes a rapid response in the brain by targeting the glutamate system’s N-methyl-D-aspartate (NMDA) receptors, quickly inhibiting the excessive release of glutamate. This, in turn, increases brain-derived neurotrophic factor (BDNF), a protein that stimulates brain plasticity. Targeting the NMDA receptors may also impact the regulation of the stress response, emotional processing, and cognition.

Research into ketamine treatment for mental health conditions is ongoing, but a growing body of evidence supports ketamine therapy as an effective option for people experiencing depression, anxiety, and PTSD symptoms.

A 2024 study found that ketamine can be effective for chronic and treatment-resistant depression and PTSD. The study authors suggest that ketamine therapy can offer an alternative for individuals who haven’t responded to conventional treatments.

J. Liu, et al. 2024
repair-brain-img
ssri-image

Advantages over SSRIs

The goal of selective serotonin reuptake inhibitors (SSRIs) and many other traditional antidepressants is to balance brain chemistry by targeting specific neurotransmitters like serotonin. However, SSRIs can take weeks to be effective, often come with uncomfortable side effects, and they don’t work well for many people.

Ketamine’s rapid action on glutamate means it can relieve depression and anxiety symptoms much faster than traditional antidepressants. Because ketamine works to repair the brain’s structure and encourage the growth of new neurons, it’s often effective for people who’ve tried other medications without success. And the increase in brain plasticity associated with ketamine therapy supports long-lasting healing and long-term change.

Am I a candidate?arrow-yellow

A literature review published in the Journal of Clinical Psychiatry found that lower doses of oral ketamine can offer similar benefits for people with depression and anxiety at a lower cost compared to higher doses of oral and IV ketamine.

C. Andrade. 2019

The Horizon dose experience

At higher doses, ketamine’s effect on NDMA receptors can disrupt sensory processing, often leading to hallucinations or a sensation of detaching from the body. However, mid-range Horizon doses aren’t dissociative or hallucinogenic. Instead, they produce gentle yet impactful experiences, guiding you toward meaningful shifts in perception, making you feel calmer, more grounded, and less reactive. The relaxation and introspection brought on by Horizon-range ketamine therapy allow you to quiet your mind, release negative thought patterns, and gain valuable insights supporting positive growth over time.

Explore our FAQ to learn more about
the ketamine experiencearrow-yellow

In a small clinical trial focused on low-dose, oral ketamine for suicidal ideation, 69% of participants taking oral ketamine experienced clinical improvement in symptoms within 6 weeks of treatment. After 10 weeks, 50% reported significant reduction of suicidal ideation.

A. Can, et. al, 2021

horizon-img
horizon-img

Mid-range ketamine:
safe and effective

Ketamine is FDA-approved for use as a surgical anesthetic. It’s been used in hospital settings for more than 50 years. In the last few decades, a growing body of evidence supports ketamine as a safe treatment for depression and other mental health conditions when administered by a licensed physician.

Horizon-dose ketamine provides a safer alternative to the high doses administered at IV clinics or through certain online providers. Recent studies show that low-dose ketamine therapy has fewer side effects while providing similar benefits.

Read about our ketamine therapy programarrow-yellow

Oral and nasal ketamine offer similar benefits compared to IV ketamine, including rapid relief for depression. According to a 2015 review, oral and intranasal ketamine reduced depressive symptoms as quickly as IV administration, with fewer side effects.

P. Twohig and V. Huckfeldt, 2015