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Unlock The Power Of Ketamine

It's all in the science

Why is ketamine therapy so effective? Can it really help with depression, anxiety, and PTSD? How does it work?

Ketamine induces profound changes inside the brain, stimulating neural processes related to neuroplasticity and learning.
It can effectively help the brain regenerate and adapt to change.

Repair your brain,
improve your mood fast

Depression, anxiety, and PTSD are associated with chronic stress, a loss of synaptic connections in key brain regions, and changes in neural circuits. Ketamine works differently than traditional antidepressants by rapidly increasing the growth and density of neurons and synapses. This glutamate system activation contributes to learning, memory, and mood regulation.

Ketamine causes a rapid expansion in the brain by targeting the glutamate system to amplify neuroplasticity (NMDA) receptors, quickly initiating the growth of new neural connections. This process is called synaptogenesis.

Research from ketamine treatment for mental health conditions is ongoing, but a growing body of evidence suggests ketamine therapy is an effective option for people experiencing depression, anxiety, and PTSD symptoms.

A 2024 study found that ketamine can be effective for chronic and treatment-resistant depression and PTSD. The study authors suggest that ketamine therapy can offer an alternative for individuals who haven’t responded to conventional treatments.

J. Liu, et al. 2024

Advantages over SSRIs

The goal of ketamine treatment is to induce neuroplasticity and rewire neural pathways associated with depression and anxiety. Unlike traditional antidepressants that can take weeks or months to be effective, many people who use ketamine report feeling better within hours.

Ketamine's rapid action on glutamate levels is far more effective and direct than SSRIs, which focus on serotonin neurotransmitters. Because of how quickly ketamine works, it can be a game-changer for people who are having thoughts of suicide or are dealing with severe, treatment-resistant depression.

J. Liu, et al. 2024

The low-dose ketamine experience

At higher doses, ketamine offers an NMDA antagonist and affects sensory perception. However, at the low doses used in Mindscape Rx's treatment, it functions as a treatment for depression, anxiety, and PTSD.

At lower doses, the effects of ketamine are much more subtle. People experience subtle shifts in perception and typically report feeling calmer, more grounded, and less anxious. The relaxation and introspection brought on by low-dose ketamine allows many people to process difficult emotions, gain new perspectives, and gain insights about their lives.

In a small clinical trial focused on low-dose, oral ketamine for suicidal ideation, 69% of participants taking oral ketamine experienced clinical improvement in symptoms within 6 weeks of treatment. After 10 weeks, 50% reported significant reduction of suicidal ideation.

A. Can, et. al, 2021

Low-dose ketamine: safe and effective

Ketamine is FDA approved for use as a surgical anesthetic. It's been used for over 50 years for this purpose. In the last two decades, it's gained traction as a treatment for mood disorders when administered in much lower doses under medical supervision.

Low-dose ketamine produces a mild dissociative effect that typically lasts 45 minutes to 2 hours. Unlike other psychedelics, ketamine does not cause hallucinations or severe alterations in consciousness at low doses.